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  • Küçük Resim
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    Retrospective clinical and laboratory evaluation of children with brucellosis
    (Wiley, 2012) Okur, Mesut; Erbey, Fatih; Bektaş, Mehmet Selçuk; Kaya, Avni; Doğan, Murat; Acar, Mehmet Nuri; Uzun, Hakan
    Background: Acute brucellosis is a zoonotic disease seen in childhood, with non-specific complaints and clinical findings that can affect the locomotor, gastrointestinal, genitourinary, hematologic, cardiovascular, respiratory, and central nervous systems. Particularly in endemic regions, it occurs as a result of consumption of unpasteurized milk and dairy products. In this study, clinical and laboratory findings of children with acute brucellosis are presented. Methods: Data for 147 patients, aged 2-16 years, were evaluated retrospectively. Results: The most frequent complaints and clinical findings were abdominal pain and fever. Other complaints and clinical findings included arthralgia, myalgia, loss of appetite, weakness, sweating, fatigue, headache, arthritis, hepatomegaly, and splenomegaly. Anemia was the most frequent hematological abnormality detected; other abnormalities included leukopenia, thrombocytopenia, and pancytopenia. Conclusion: Childhood brucellosis can cause non-specific complaints and particularly anemia and leukopenia as hematological abnormalities. It is easily treated, however, with appropriate antibiotics.
  • Küçük Resim
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    The Seropositivity Of Hepatitis A In Children Between 0-18 Years In The Van Province And Around
    (Düzce Üniversitesi, 2011) Erbey, Fatih; Acar, Mehmet Nuri; Güven, Ayşe; Kaya, Avni; Okur, Mesut
    Aim: The aim of this study is to determine Hepatitis A virus (HAV) seropositivity in Vanprovince and around.Material and Methods: During January 2007- December 2008, 3409 patients with hepatic ornon-hepatic symptoms and a mean age of 7 ± 4.3 years (between 0-18 years) were examinedretrospectively for anti HAV IgG and anti HAV IgM at the outpatient clinics of Pediatrics inVan Women’s and Children’s Hospital. Patients were divided into five groups which were 0-2,3-5, 6-10, 11-15 years and over 15 years groups. In each group, HAV incidence andseropositivity were determined .Results: The anti-HAV IGM and anti-HAV IgG seropositivity rates were found to be 15.3 %(524/3409) and 69.9 % (2384/3409), respectively. The seropositivity rate of HAV increasedsignificantly with age, and the highest rate of HAV IgM positivity is observed between the agesof 3-10.Conclusion: In our region, HAV seropositivity is high. Hence, the improvement of hygenicconditions, educational and socio-economical status of parents and public education abouthepatitis A vaccine are a necessity