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    Effects of Smoking on Pattern Visual Evoked Potentials
    (Tıbbi Kayıtlar Derneği, 2023) Eski, Mehmet Tahir; Yabalak, Ahmet; Şahan, Halime; Ayaslı, Alper; Sezer, Taha
    Aim: The aim of the study is to get a better understanding of the side effects of smoking by evaluating the effect of recently elevated smoking rate on Visual Evoked Potentials (VEP) and to determine whether it is necessary to use different normals when evaluating the VEP measurements of smoking patients. Material and Methods: The patients who have applied to our ophthalmology and neurology outpatient clinics during 2021-2022 are included to the study. Detailed ophthalmologic examination of the patients as well as their VEP test is completed followed by a dilated fundus examination assessment. The patients with normal results are included to the study. The smoking rate is calculated on pack/year basis. Pattern VEP (PVEP) recording is performed based on Keypoint (Dantec, Denmark) and International Society for Clinical Electrophysiology of Vision (ISCEV) criteria. Data obtained through the study are analyzed by SPSS 21.0 version software. Countable variables with normal distribution between two independent groups are analyzed with Independent Sample T test whereas variables without normal distribution are analyzed with Mann Whitney U test. Chi-square test is used for comparing categorical variables. Results: 71 patients were included to the study where 33 of them were placed in smoking group and 38 in non-smoking group (control group). Smoking group had a yearly cigarette package consumption of 5.20±8.93 (0.2-40). VEP latency and amplitude changes were compared and according to the obtained results; there was P100 latency prolongation in between left and right eye of the patients in the control group and smoking group but it did not have any statistical significance (p=0.910 and p=0.697 respectively). There was no statistically significant difference in either left nor right eye in terms of smoking and P100 and N70 latencies (p=0.707, p=0.838, p=0.717 and p=0.621 respectively). Similarly, there was no significant correlation between yearly package consumption and P100 and N70 latencies and amplitudes of left and right eyes (p=0.503, p=0.410, p=0.776 and p=0.940 respectively). Conclusion: No significant effect of smoking is found on VEP values thus leading us to believe that the same normal intervals can be used in the evaluation of VEP results of both smoking and non-smoking patients.

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