Yazar "Üstün, Cemal" seçeneğine göre listele
Listeleniyor 1 - 14 / 14
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe A Case of Asymptomatic Hepatitis A virus infection(Düzce Üniversitesi, 2007) Kara, İsmail Hamdi; Üstün, Cemal; Geyık, Mehmet Faruk; Dıkıcı, BünyaminHepatitis A infection is a common infectious disease seen especially in children of developing countries. Personal contact is very considerable among the fecal-oral contagious diseases. A 11-yearsold girl, referring to outpatient clinics of department of family medicine, has the history of contact with her hepatitis A infected friend. Flu-like symptoms arose in 15 days after the contact. Any abnormal parameter except anti-HAV Ig M positiveness wasn’t detected in the laboratory studies. Biochemical parameters were reported as normal during the one-year period of routine control. It was assigned that anti-HAV Ig M, being positive since the beginning of the disease, turned to negative in the 12th month. Because no hepatitis A case after a contact history was established in the literature, existing case was distinguished to presentÖğe The accuracy and validity of a weekly point-prevalence survey for evaluating the trend of hospital-acquired infections in a university hospital in Turkey(Elsevier Sci Ltd, 2011) Üstün, Cemal; Hoşoğlu, Salih; Geyik, Mehmet Faruk; Parlak, Zafer; Ayaz, CelalObjective: To evaluate the validity of a weekly point-prevalence survey (WPS) by comparing it with a prospective-active incidence survey (PIS). Methods: WPS and PIS were conducted at a tertiary referral hospital between January and December 2006. Each Wednesday, an infection control team reviewed all clinical records of patients with hospital-acquired infections (HAIs) by WPS. Routine PIS was conducted with daily visits by the same team. The Rhame and Sudderth formula was used for converting the data between WPS and PIS. Results: During the study period, 1287 HAIs were detected in 37 466 patients by WPS. The mean observed prevalence and calculated prevalence were 5.42% and 5.45%, respectively. The reanimation intensive care unit (ICU) (49.4%) and burns unit (27.6%) had the highest prevalence rates. Pneumonia (0.94%) and urinary tract infections (0.37%) were the most frequent infections. Overall 602 HAIs were detected in 545 patients by PIS. The mean observed incidence and calculated incidence were 2.42/1000-admissions and 2.41/1000-admissions, respectively. The Critical care ICU (37.0/1000-admissions) and burns unit (24.8/1000-admissions) had the highest incidences of HAI. Pneumonia (0.64/1000-admissions) and urinary tract infections (0.37/1000-admissions) were the most frequent infections. Conclusions: This study confirms a close relationship between prevalence and incidence data. WPS may be a useful method for following HAIs when PIS cannot be performed. (C) 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.Öğe Alterations of Serum Copper and Zinc Levels, and Copper/Zinc Ratios Among Patients with Brucellosis(Ortadogu Ad Pres & Publ Co, 2012) Üstün, Cemal; Teğin, İbrahim; Geyik, Mehmet FarukObjective: To determine the alterations of serum copper (Cu) and zinc (Zn) levels and Cu/Zn ratio in patients with brucellosis. Material and Methods: A total of 170 individuals were included in the study. Of these, 45 (26.5%) currently had acute or sub-acute brucellosis, 35 (20.6%) were previously diagnosed with acute or sub-acute brucellosis and successfully treated, and 90 (52.9%) were healthy volunteers. After fasting overnight for 10 hours, 5 ml of venous blood was taken from all subjects. Serum Cu and Zn levels were measured using a Unicam 929 Atomic Absorption Spectrophotometer. SPSS 16.0 was used for data analysis. Results: Mean serum Cu levels of 45 patients with acute or sub-acute brucellosis, 35 patients previously diagnosed with acute or sub-acute brucellosis and 90 healthy volunteers were 88.6 +/- 26, 58.7 +/- 13 and 56.7 +/- 16 mu g/dL, respectively. Mean serum Zn levels of 45 patients with acute or sub-acute brucellosis, 35 patients previously diagnosed with and treated successfully for acute or sub-acute brucellosis and 90 healthy volunteers were 38.3 +/- 12, 58.5 +/- 14, and 55.8 +/- 13 mu g/dL, respectively. Serum Cu levels (p<0.001) and Cu/Zn ratios (p<0.001) were statistically significantly higher while serum Zn levels (p<0.001) were lower in patients with acute or sub-acute brucellosis when compared to the individuals who previously diagnosed with acute or sub-acute brucellosis and the healthy volunteers. Conclusion: This study revealed significant alterations of serum Cu and Zn levels, and Cu/Zn ratios in patients with acute or sub-acute brucellosis. Serum Cu, Zn, and Cu/Zn ratios may be available biomarkers in the course of acute or sub-acute brucellosis.Öğe Brain abscess due to proteus mirabilis meningitis as a complication of mastoiditis: Case report(2010) Önen, Mehmet Reşit; Üstün, Cemal; Geyik, Mehmet FarukMeningitis and intracranial abscess due to Proteus mirabilis is seen especially in the neonatal period and among the patients with immune deficiency. It was learned that 35 years old male patient who applied to the emergency room with ongoing fever, nausea and vomiting for three days have had their upper left jaw tooth out 10 days ago. As clinical and laboratory to patients with acute bacterial meningitis empirical ceftriaxone 2x2 gr/day parenteral was started. The cranial MR of the patient, that has P. mirabilis producing in their blood and cerebrospinal fluid (CSF) culture, was taken at the seventh day of hospitalization as his complaints started again. In the MR, abscess was detected in the left temporal brain of the patient and a surgical treatment was applied. Complete healing was seen eight week treatment with antibiotics after surgery. During application it was though that meningitis has occurred due to the dental surgery, however after the temporal BT, mastoiditis was detected. It was thought that meningitis and brain abscess developed on the patient was caused by mastoiditis. Even with sensitive antibiotics if no recovery is observed in patients with meningitis, intracranial abscess should be considered, also it should not be forgotten that in adults and patients with no immune deficiency meningitis due to P. mirabilis may develop. © 2010 Düzce Medical Journal.Öğe Braın Abscess Due To Proteus Mirabilis Meningitis As A Complication Of Mastoiditis: Case Report(Düzce Üniversitesi, 2010) Üstün, Cemal; Geyik, Mehmet Faruk; Önen, Mehmet ReşitMeningitis and intracranial abscess due to Proteus mirabilis is seen especially in the neonatalperiod and among the patients with immune deficiency. It was learned that 35 years old malepatient who applied to the emergency room with ongoing fever, nausea and vomiting for threedays have had their upper left jaw tooth out 10 days ago. As clinical and laboratory to patientswith acute bacterial meningitis empirical ceftriaxone 2x2 gr/day parenteral was started. Thecranial MR of the patient, that has P. mirabilis producing in their blood and cerebrospinal fluid(CSF) culture, was taken at the seventh day of hospitalization as his complaints started again.In the MR, abscess was detected in the left temporal brain of the patient and a surgical treatmentwas applied. Complete healing was seen eight week treatment with antibiotics after surgery.During application it was though that meningitis has occurred due to the dental surgery, howeverafter the temporal BT, mastoiditis was detected. It was thought that meningitis and brain abscessdeveloped on the patient was caused by mastoiditis. Even with sensitive antibiotics if norecovery is observed in patients with meningitis, intracranial abscess should be considered, alsoit should not be forgotten that in adults and patients with no immune deficiency meningitis dueto P. mirabilis may developÖğe A case of brucellar spondylodiscitis involving the cervical spine(Ios Press, 2009) Nas, Kemal; Bükte, Yaşar; Üstün, Cemal; Çevik, Remzi; Geyik, Mehmet Faruk; Batmaz, İbrahimWe have presented a patient of 71-year-age with brucellar spondylodiscitis, involving the cervical spine, especially the C3-C4 segment. The patient had painful percussion of the cervical spine and passive mobilization of the neck, decreased range of motion, and cervical paravertebral tenderness; but no abnormalities observed on neurological examination. Wright agglutination test for brucella was positive at 1/320. Cervical localization for brucellar spondylodiscitis is an unusual case and should be detected and treated as early as possible. In endemic regions, spinal involvement of brucellosis should be considered in cases with fever, neck and low back pain.Öğe The effects of snake venom on serum copper, zinc and magnesium levels in patients with snake bite(2013) Üstün, Cemal; Teğin, İbrahim; Geyik, Mehmet FarukAmaç: Yılan ısırıkları Türkiye'nin doğu ve güneydoğu bölgelerinde sık görülen önemli bir problemdir. Bu çalışmada yılan ısırığı vakalarında serum bakır (Cu), çinko (Zn) ve magnezyum (Mg) düzeylerindeki değişiklikler araştırıldı.Yöntemler: Çalışmaya 40 yılan ısırıklı hasta ile kontrol amaçlı 80 sağlıklı gönüllü alındı. Yaklaşık 10 ml venöz kan çalışmaya alınan her bir bireyden alındı. Serum eser element düzeyleri Atomik Absorbsiyon Spektormetre cihazı kullanılarak ölçüldü. Bulgular: Çalışmaya alınan 40 yılan ısırıklı hastanın yaş ortalaması 40,1 12 yıl olup, 18'i (% 45) erkek idi. Sağlıklı 80 bireyin yaş ortalaması 40,6 10 yıl olup, 36'sı (% 45) erkek idi. Yılan ısırıklı hastaların serum Cu, Zn, ve Mg düzeyleri sırasıyla 75,8 20,9; 86,9 25,2 ve 1201 562 µg/dL bulundu. Sağlıklı gönüllülerin serum Cu, Zn, and Mg düzeyleri sırasıyla 57,6 17,2; 55,8 12,4 ve 1454 278 µg/dL bulundu. İstatistiksel olarak sağlıklı gönüllüler ile karşılaştırıldığında, yılan ısırıklı hastaların serum Cu ve Zn düzeylerinde anlamlı bir artış (p 0.001) ve serum Mg düzeylerinde anlamlı bir düşüş (p0,001) saptandı.Sonuç: Yılan zehiri, yılan ısırığı olan hastaların serum Cu, Zn ve Mg düzeyleri üzerinde anlamlı değişimler oluşturmaktadır. Yılan zehrinin serum eser element düzeylerinde oluşturduğu bu değişimlerin ileri düzey çalışmalarla araştırılması yılan ısırığı olan hastaların tedavisinde yeni gelişmeler sağlayabilir.Öğe The efficacy of dexamethasone treatment in massive enteric bleeding in typhoid fever(Sage Publications Inc, 2009) Hoşoğlu, Salih; Üstün, Cemal; Geyik, Mehmet Faruk…Öğe Mastoiditin komplikasyonu sonucu gelişen proteus mirabilis menenjitine bağlı beyin absesi: olgu sunumu(2010) Önen, Mehmet Reşit; Üstün, Cemal; Geyik, Mehmet FarukProteus mirabilis’e bağlı menenjit ve intrakraniyal apse gelişimi, özellikle neonatal dönemde ve immün yetmezliği olan bireylerde görülmektedir. Acil servise; üç gündür devam eden ateş, bulantı ve kusma yakınmalarıyla başvuran 35 yaşında erkek hastanın, 10 gün önce sol üst çeneden diş çektirdiği öğrenildi. Klinik ve laboratuar olarak akut bakteriyel menenjit ile uyumlu olan hastaya ampirik seftriakson 2x2 gr/gün parenteral başlandı. Kan ve beyin omurilik sıvısı (BOS)’nda P. mirabilis üreyen hastanın; yatışın yedinci gününde yakınmalarının tekrar başlaması üzerine, kranial MR çekildi. MR’da sol temporalde beyin apsesi saptanan hastaya cerrahi tedavi uygulandı. Cerrahi sonrası sekiz haftalık antibiyotik tedavisi ile tamamen iyileşme görüldü. Başvuru sırasında menenjitin dental cerrahiye bağlı oluştuğu düşünülen hastada, daha sonra çekilen temporal BT sonrası mastoidit tespit edildi. Olguda gelişen menenjit ve beyin absesinin mastoidite bağlı olduğu düşünüldü. Menenjit olgularında, duyarlı antibiyotiğe rağmen düzelme saptanmaması durumunda intrakranial apse düşünülmeli, erişkin ve immün yetmezliği olmayan olgularda da P. mirabilis’e bağlı menenjit gelişebileceği unutulmamalıdır.Öğe Risk Factors for Multi-Drug-Resistant Pseudomonas aeruginosa Infections in a University Hospital-A Case Control Study(Duzce Univ, 2016) Üstün, Cemal; Hoşoğlu, Salih; Geyik, Mehmet FarukPurpose: This study aims to determine the risk factors associated with multi-drug-resistant Pseudomonas aeruginosa (MDR-Pa) infections. Methods: A case control study was conducted at the Dicle University Hospital which is 1150-bed tertiary care teaching hospital in Diyarbakir, Turkey. The study cases were recruited from patients with nosocomial MDR-Pa infections. Two control cases were arranged to compare risk factors of MDR-Pa infections. One of the control groups was composed of patients with non-MDR-Pa infections and the other group with non-MDR Gram-negative bacterial infections except P. aeruginosa. Results: Overall, 225 patients were included in the study, 75 with MDR-Pa infections, 150 control cases (75 non-MDR-Pa and 75 MDR Gram-negative non P. aeruginosa infections). The incidence of MDR-Pa infections was found as 3.1/1,000 admissions. Multivariate analysis showed that multiple invasive procedures (Relative Risk 24.57 (95% Confidence Interval 4.45-135.73) p<0.001), burn (RR 13.66 (CI 407-45.80) p<0.001), malignity (RR 12.50 (CI 2.64-59.20) p=0.001), pneumonia (RR 11.91 (CI 2.44-58.16) p=0.002), carbapenem use (RR 4.92 (CI 1.60-15.09) p=0.005) and long hospitalization (>10 days) (RR 4.68 (CI=2.09-10.49) p<0.001), were found to be risk factors for MDR-Pa. Conclusions: This study revealed that severity of clinical course and carbapenem use are significant risk factors for MDR-Pa infections.Öğe The Role of Trace Elements in Helicobacter Pylori Infected Patients(Kuwait Medical Assoc, 2011) Bozkurt, Fatma; Gülsün, Serda; Üstün, Cemal; Geyik, Mehmet Faruk; Hoşoğlu, SalihObjective: To evaluate the effect of trace elements in patients with Helicobacter pylori associated chronic gastritis Design: Prospective study Settings: Clinical services of the clinical microbiology and infectious diseases and gastroenterology clinics at Dicle University, Turkey Subjects:A total of 92 patients with variable severity of chronic gastritis (45 Helicobacter pylori positive and 47 Helicobacter pylori negative gastritis) and 90 age and sex matched healthy subjects were included in the study conducted between October 2006 and November 2008. Intervention: Histopathologic examination, culture of Helicobacter pylori and urease tests were performed for each patient. The atomic absorption spectrophotometer was used in the measurement of trace elements in the serum. Main Outcome Measures: Serum copper and zinc levels were significantly elevated in patients with Helicobacter pylori associated gastritis compared to Helicobacter pylori negative gastritis and healthy controls (p < 0.0001). Serum copper, zinc and Cu / Zn levels in patients with Helicobacter pylori negative chronic gastritis was not significantly different from the serum levels in healthy controls (p > 0.05). Conclusions: Our results suggest a relationship between Helicobacter pylori associated chronic gastritis and the elevation of trace element levels in serum. This study confirms that the elevation of trace element levels in serum (Cu and Zn levels) will be helpful in the diagnosis of Helicobacter pylori associated chronic gastritis in the abscence of invasive procedures, and is useful in predicting the severity of infection in patients with chronic gastritis.Öğe The role of trace elements in wagner classified diabetic patients(Academic Journals, 2011) Bozkurt, Fatma; Gülsün, Serda; Üstün, Cemal; Geyik, Mehmet Faruk; Teğin, İbrahim; Satıcı, ÖmerWagner's classification is the most widely used grading system in diabetic foot infections. The aim of this study was to evaluate the role of the trace elements in diabetic foot infected patients graded with Wagner's classification. This prospective study was carried out on 50 diabetic patients with variable severity of foot infections and 50 age and sex matched healthy subjects in Dicle University, Turkey, between October 2006 and November 2008. Diabetic foot infections were graded according to Wagner classification and deep tissue cultures were performed from all diabetic foot infected patients. The atomic absorption spectrophotometer was used in the measurement of trace elements in the serum. serum zinc and copper levels were significantly elevated in patients with Wagner 3 and 4 compared to Wagner 2 and 1 graded patients and healthy controls. Also Wagner 1 and 2 graded patients had higher serum zinc levels compared to healthy controls (p < 0.001). This study confirms that trace elements may be used as a leading sign to determine the severity of infections in diabetic foot wounds and may be used to predict outcome of diabetic foot infections.Öğe Surveillance of Nosocomial Infections in Dicle University Hospital: a Ten-Year Experience(Tubitak Scientific & Technical Research Council Turkey, 2008) Geyik, Mehmet Faruk; Hoşoğlu, Salih; Ayaz, Celal; Çelen, Mustafa Kemal; Üstün, CemalAim: The main objective was to recognize the evaluation of surveillance program on the nosocomial infections (NIs) in Dicle University Hospital (DUH) Materials and Methods: A prevalence study was performed prospectively, at the DUH from 1997 to 2006. Active surveillance for NIs were performed by infection control team, using the criteria proposed by the Centers for Diseases Control and Prevention (CDC) and National Nosocomial Infections Surveillance System (NNIS) methodology. This team includes infection control doctor and two nurses, who visited hospital units three times a week. All cases with NI were recorded using a standard data collection form. Results: During ten years of follow up period, 3382 NI episodes were detected in 3075 patients out of 250209 inpatients. The overall incidence rates (NI/100) and incidence densities (NI/1000 days of stay) of NIs were 1.4% (range 0.8-2.5/100) and 1.7/1000 patients-days (range 0.7-2.5/1000), respectively. NIs were seen frequently in intensive care unit (20.1 episodes per 1000 bed-days), burn unit (14.5 episodes per 1000 bed-days), and neurology (3.7 episodes per 1000 bed-days). The most common NIs according to the primary sites were urinary tract infection (24%), bloodstream infection (22%), pneumonia (13%) and surgical site infection (13%). The most prevalent microorganisms were Escherichia coli (26%), Pseudomonas aeruginosa (15%), coagulase-negative staphylococci (14%) and Staphylococcus aureus (13%). Amikacin and meropenem were the most effective agents against Gram-negative bacteria. Meticillin resistance among S. aureus isolates was 67% and all were sensitive to vancomycin. Conclusions: This study represents that the rate of NIs reduced with appropriate interventions. Surveillance and constant monitoring are effective along with educating the staff about infection control practices.Öğe Surveillance of nosocomial infections in general surgery unit: Data of ten years period(2010) Üstün, Cemal; Geyik, Mehmet Faruk; Aldemir, Mustafa; Tekin, Recep; Çelen, Mustafa Kemal; Girgin, Sadullah; Ayaz, CelalAim: The aim of this study is to evaluate the epidemiologic data of nosocomial infection (NI) occurring in the General Surgery Unit (GSU). Method: This study was performed between January 1997 and December 2006. The surveillance method was active, prospective, and based on laboratory and patient. NIs were defined according to Centers for Diseases Control and Prevention criteria (CDC). Results: During the ten-year period, 305 NI episodes were detected in 290 patients. The overall incidence rates and incidence densities of NIs were 2.0% and 2.3/1,000 patient-day respectively. The most common NIs by primary site were surgical site infections, urinary tract infections, and pneumonia. The most prevalent microorganisms were Escherichia coli (36.8%), Staphylococcus aureus (17.7%) and Pseudomonas aeruginosa (10.5%). Meticillin resistance among S. aureus isolates was 76%. Meropenem and amikacin were the most effective agents against to Gram-negative bacteria. Conclusion: In order to detect of the variation and trends of NIs, the data of surveillance activities must be evaluated decisively and regularly with collaboration among infection control team, Infectious Disease clinic, and GSU. © 2010 Düzce Medical Journal.
