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Öğe The 2100 MHz radiofrequency radiation of a 3G-mobile phone and the DNA oxidative damage in brain(Elsevier Science Bv, 2016) Şahin, Duygu; Özgür, Elçin; Güler, Gülnur; Tomruk, Arın; Ünlü, İlhan; Dinçel, Aylin Sepici; Seyhan, NesrinWe aimed to evaluate the effect of 2100 MHz radiofrequency radiation emitted by a generator, simulating a 3G-mobile phone on the brain of rats during 10 and 40 days of exposure. The female rats were randomly divided into four groups. Group I; exposed to 3G modulated 2100 MHz RFR signal for 6 h/day, 5 consecutive days/wk for 2 weeks, group II; control 10 days, were kept in an inactive exposure set-up for 6 h/day, 5 consecutive days/wk for 2 weeks, group III; exposed to 3G modulated 2100 MHz RFR signal for 6 h/day, 5 consecutive days/wk for 8 weeks and group IV; control 40 days, were kept in an inactive exposure set-up for 6 h/day, 5 consecutive days/wk for 8 weeks. After the genomic DNA content of brain was extracted, oxidative DNA damage (8-hydroxy-2'deoxyguanosine, pg/mL) and malondialdehyde (MDA, nmoL/g tissue) levels were determined. Our main finding was the increased oxidative DNA damage to brain after 10 days of exposure with the decreased oxidative DNA damage following 40 days of exposure compared to their control groups. Besides decreased lipid peroxidation end product, MDA, was observed after 40 days of exposure. The measured decreased quantities of damage during the 40 days of exposure could be the means of adapted and increased DNA repair mechanisms. (C) 2016 Elsevier B.V. All rights reserved.Öğe Arsenic related hearing loss in miners(W B Saunders Co-Elsevier Inc, 2016) Kesici, Gülin Gökçen; Ünlü, İlhan; Topçu, Arzu Baştürk; Bal, Ceylan Demir; Tutkun, Engin; Yılmaz, Ömer HınçPurpose: Arsenic is a toxic metalloid that carries number of potential risks to human health, although there is little evidence of the ototoxic effect of arsenic. The aim of this study was to identify the relationship between arsenic exposure and hearing loss by measuring blood arsenic concentrations and hearing among miners. Materials and methods: This research is a retrospective case control study. Included in the study were miners employed in a single silver mine whose blood arsenic concentrations were high. A comparison was made on the pure tone audiometry measurements taken from miners exposed only to arsenic (Group 1), those exposed to both arsenic and noise (Group 2) and a control group exposed to neither arsenic nor noise (Group 3). Results: It was found that for both ears at all frequencies, the hearing level of Group 3 was better than the hearing levels of both Group 1 and Group 2. There was no correlation between the blood arsenic levels and hearing levels in both ears. Conclusion: This study has revealed the ototoxic effects of arsenic. As blood arsenic concentrations do not reflect long-term exposure, no correlation was identified between blood arsenic concentrations and hearing levels. Further studies will be needed to clarify the mechanisms involved in the effect of arsenic on hearing. This paper represents the largest study to date focusing on the isolated effects of arsenic on hearing through the use of a clinical auditory test. (C) 2016 Elsevier Inc. All rights reserved.Öğe The Association between Iron Deficiency and Otitis Media with Effusion(Aves, 2019) Akcan, Fatih Alper; Dündar, Yusuf; Akcan, Hümeyra Bayram; Cebeci, Derya; Sungur, Mehmet Ali; Ünlü, İlhanOBJECTIVES: The purpose of this trial is to examine the clinical role of iron metabolism on development of Otitis media with effusion. MATERIALS and METHODS: This prospective study was conducted in a tertiary referral center. The study group made up of children who had surgery for Otitis media with effusion (OME). Control group was comprised of children who had surgery by a pediatric surgeon for inguinal hernia repair or circumcision operations with normal ear nose throat examination. Each group was evaluated depending on the serum iron metabolism parameters. RESULTS: One-hundred-thirteen children with OME and 117 control patients were included to the study. Iron deficiency anemia was detected in 18 out of 113 patients (15.9%) in study group while there were 4 out of the 117 patients (3.4%) in control group (p:0.001). The mean hemoglobin level was 12.16 +/- 1.16 in OME group and 12.93 +/- 1.08 in control group (p<0.001). CONCLUSION: The current study shows the rate of iron deficiency anemia is higher in patients with OME than controls. Iron-deficiency anemia might be considered a potential risk factor for development of otitis media with effusion, and iron parameters should be evaluated in these children.Öğe A Case of Rare Anatomic Variation: Bifid Inferior Turbinate(2023) Ozbulat, Bahadır; Ünlü, İlhanThere are 3 pairs of turbinates defined: superior, middle, and inferior. They are located throughout the lateral walls of the nasal cav- ity. The embryological evolution of the nasal turbinate is a complex process. During the embriologic development of nasal turbi nate, anatomic variations may appear at multiple points. There are very few publication about this topic. Bifid inferior turbinate is a very r are abnormality that is easily identified on paranasal tomography but should be looked on endoscopy. We have one case about bifid inferior turbinate. This variation should be kept in mind as a rare cause of nasal obstruction. We have found that surgical treatment is very beneficial this patients.Öğe Clinical importance of preoperative fine needle aspiration biopsy and computed tomography in parotid gland masses(2016) Şahin, Ender; Ünlü, İlhan; Ünlü, Elif Nisa; Kaptan, Zeynep; Uzunkulaoğlu, Hakkı; Samim, Ethem Erdal; Karadavut, YunusObjectives. To determine the diagnostic value of fine needle aspiration biopsy (FNAB) and computedtomography (CT) in parotid masses in the basis of postoperative histopathological results. Methods. The recordsof 68 patients diagnosed with a parotid mass and undergone parotis surgery between November 2004 andFebruary 2011 were evaluated retrospectively. Preoperative FNAB and the CT findings were compared withpostoperative histopathological findings. Results. The study included 36 (58%) female and 26 (42%) malepatients. The mean age of the patients was 43.9 years. No statistically significant difference was detected withregards to the performances of both FNAB and the CT (p0.797). When it was evaluated in a detail, theperformance of parotid CT(81.82%) to diagnose a mass in parotid gland was relatively better than FNAB(72.73%). The performance of FNAB (94.12%) to detect healthy ones was also greater than parotid CT (90.2%).Conclusion. We emphasize that preoperative FNAB and parotid CT should be performed to the patients witha parotid mass. The use of these two tests together can minimize the risk rate have been proved.Öğe Clinical role of vitamin D in prognosis of otitis media with effusion(Elsevier Ireland Ltd, 2018) Akcan, Fatih Alper; Dündar, Yusuf; Akcan, Hümeyra Bayram; Uluat, Ahmet; Cebeci, Derya; Sungur, Mehmet Ali; Ünlü, İlhanObjective: To investigate the clinical role of Vitamin D in prognosis of Otitis media with effusion. Methods: This prospective-controlled study was conducted at otolaryngology department in Duzce University, Turkey. The study group comprised children who were diagnosed with Otitis media with effusion between September 2016 and February 2017. Control group was conducted with children underwent circumcision or inguinal hernia repair operations that confirmed with ENT examination they do not have any sign of otitis media. After 3 months of follow-up without any treatment, unresolved cases who were accepted as chronic otitis media with effusion were operated under general anesthesia for ventilation tube application. Study and control groups were assessed depending on the serum 25(OH)Vitamin D levels at the end of 3 months; <15 ng/mL was accepted as vitamin D deficiency. The results were compared with the control group in terms of vitamin D levels. Also, subgroup analysis was performed addressing to the complete recovery otitis media with effusion and chronic otitis media with effusion. Results: One-hundred-seventy-four children with otitis media with effusion and 80 control patients were included to the study. One-hundred-eight (62%) out of 174 patients with otitis media with effusion was completely recovered after a 3-months follow up. Of those 66 out of 174 children, they had persistent diseases, underwent ventilation tube insertion after a 3-months follow-up. The mean 25(OH)Vitamin D level was 18.98 +/- 10.60 in otitis media with effusion group and 28.07 +/- 14.10 in control group and the difference was statistically significant between the study and control group (p < 0.001). Vitamin D deficiency was observed in 33 out of 66 patients (50.0%) in chronic otitis media with effusion group whilst 35 out of 108 patients (32.4%) in complete recovery otitis media with effusion group (p = 0.021). The rate of 25(OH)Vitamin D deficiency was 25% in control group which was statistically different from chronic otitis media with effusion and recovery chronic otitis media with effusion groups (p = 0.006). Conclusions: This study not only shows the relationship between Vitamin D and otitis media with effusion development, but also demonstrates the effects of Vitamin D on otitis media with effusion prognosis. There is a significant association between 25(OH)Vitamin D deficiency and follow-up outcomes of otitis media with effusion.Öğe Comparison of effect ofvaccination against polysaccharide streptococcus pneumoniae and haemophilus influenzae and ventilation tube ino titis media with effusion(Turkiye Klinikleri, 2014) Ünlü, İlhan; Samim, Ethem ErdalObjective: Otitis media with effusion (OME) is a common childhood infection. Streptococcus pneumoniae and Haemophilus influenzae are very common bacterial pathogens in the etiology of OME. The purpose of the study is providing immunization against these pathogens and to see how it affects the course and recurrence of OME according to insert ventilation tube. Material and Methods: Ventilation tube was performed to 45 patients with OME between the ages of 2 to 13.H. influenzae type b conjugate vaccine and Pneumococcal polysaccharide vaccine containing 23 serotypes were applied together with an interval of 1 week to 35 patients between the ages of 2 to 13 who did not accept the application of ventilation tube. Patients with systemic diseases, immunodeficiency, allergy history, craniofacial malformations (for example, cleft palate, retrognathia, choanal atresia), previously application of the tube or history of ear surgery were excluded from the study. All patients were evaluated with pneumotoscopy and tympanometry at first week and at 1, 3, 6, 9, 12th months after the therapy and the findings were recorded. Results: The best results of vaccination group (VG) were obtained at the end of 12th month. Complete remission was observed in 24 (68.6%) patients and partial remission was observed in one patient at the end of 12th month. Also complete remission in 28 (62.2%) patients and partial remission in 3 (6.7%) patients was observed at the tube group (TG). Statistical analysis showed no significant difference between AT and TG in terms of healing rates (p?0.05). Conclusion: Vaccination of the patients with OME against S. pneumoniae and H. influenzae reduces the progression and recurrence of OME, but it's not more effective than ventilation tube. © 2014 by Türki ye Klinikleri.Öğe A comparison of the effects of solvent and noise exposure on hearing, together and separately(Medknow Publications & Media Pvt Ltd, 2014) Ünlü, İlhan; Kesici, Gülin Gökçen; Baştürk, Arzu; Köş, Mehmet; Yılmaz, Ömer HınçThe objective of the present study was to assess the effects of occupational exposure to noise and organic solvents on hearing loss in bus and truck plant workers. Our case control study contained 469 workers from a bus and truck plant divided into three groups. The first group contained workers exposed to only noise; the second group contained workers exposed to both noise and mixture solvents at a permissible level; and the third group included workers exposed to permissible levels of solvents. The control group (Group 4) included 119 individuals selected randomly, persons who were not exposed to noise and solvents. These groups were compared in terms of each individual's frequency hearing loss in both ears. Our study demonstrates that combined exposure to mixed solvents and noise can exacerbate hearing loss in workers. Hence, a suitable hearing protection program is advised that would contain short-interval audiometric examinations and efficient hearing protectors.Öğe The effect of 2100 MHz radiofrequency radiation of a 3G mobile phone on the parotid gland of rats(W B Saunders Co-Elsevier Inc, 2015) Aydoğan, Filiz; Ünlü, İlhan; Aydın, Emine; Yumuşak, Nihat; Devrim, Erdinç; Samim, Ethem Erdal; Seyhan, NesrinPurpose: We aimed to evaluate the effect of 2100 MHz radiofrequency radiation on the parotid gland of rats in short and relatively long terms. Material and methods: Thirty Wistar albino rats were divided into four groups. Groups A and B served as the control groups (for 10 days and 40 days, respectively), and each group included six rats. Groups C and D were composed of nine rats each, and they were the exposure groups. The rats were exposed to 2100 MHz radiofrequency radiation emitted by a generator, simulating a third generation mobile phone for 6 hours/day, 5 days/week, for 10 or 40 days. Following exposure, the rats were sacrificed and parotid glands were removed. Histopathological and biochemical examinations were performed. Results: Although there were no histopathological changes in the control groups except for two animals in group A and three animals in group B, the exposure groups C (10 days) and D (40 days) showed numerous histopathological changes regarding salivary gland damage including acinar epithelial cells, interstitial space, ductal system, vascular system, nucleus, amount of cytoplasm and variations in cell size. The histopathological changes were more prominent in group D compared to group C. There was statistically significant different parameter regarding variation in cell size between the groups B and D (p = 0.036). Conclusion: The parotid gland of rats showed numerous histopathological changes after exposure to 2100 MHz radiofrequency radiation, both in the short and relatively long terms. Increased exposure duration led to an increase in the histopathological changes. (C) 2015 Elsevier Inc. All rights reserved.Öğe The effect of duration of nasal obstruction on mean platelet volume in patients with marked nasal septal deviation(Springer, 2016) Ünlü, İlhan; Kesici, Gülin Gökçen; Öneç, Birgül; Yaman, Hüseyin; Güçlü, EnderNasal obstruction is a common cause of marked nasal septal deviation. It is related strongly with hypoxia. Hypoxic conditions increase mean platelet volume levels. This study aimed to investigate the effect of age on mean platelet volume in patients with marked nasal septal deviation. We made a retrospective study of patients with marked nasal septal deviation between January 2012 and May 2014. The patients were divided into four groups according to duration of nasal obstruction (less than 10, 10-20, 20-30 and more than 30 years). The groups were compared with each other in terms of mean platelet volume, platelet distribution width, platelet count in preoperative hemogram. This study was performed on 356 male and 139 female patients. Mean age was 33.9 +/- A 12.3 years. It was determined that the platelet count, mean platelet volume did not constitute statistically significant difference between groups (p > 0.05). Nevertheless, it was determined that as the duration of nasal obstruction elongated the mean platelet volume value increased and platelet count values decreased. Mean values of platelet distribution width constituted statistically significant difference between all groups (p = 0.026). Patients with marked nasal septum deviation should be subjected to surgery as soon as possible because of the increase in mean platelet volume and platelet distribution width values which are related to increase in the risk of cardiopulmonary complications of nasal obstruction.Öğe The effect of nasal steroids on retinal nerve fiber layer in patients with a family history of glaucoma(2023) Ünlü, İlhan; Eski, Mehmet TahirObjectives: We aimed at analyzing the effect of nasal steroids on intraocular pressure (IOP) and retinal nerve fiber layer thickness (RNFL) in patients with a family history of glaucoma who also use fluticasone propionate (FP group) and mometasone furoate (MF group). Methods: Patients with a family history of glaucoma and suitable for using nasal steroids were included in the study population. IOP, anterior chamber depth (ACD), axial length (AL) and central corneal thickness (CCT) and RNFL thickness measurements of the patients were carried out. Measurements were done on 3 levels, namely, one before starting the medication, the other 1 month after starting the medication and the last one 3 months after the medication. 3 groups were established in our study: patients who are using MF group and FP group and also C group (control group; healthy individuals who have a family history of glaucoma but not using any medication). Results: The average age of patients in our study who were under medication was 33.2 ± 8.9 years. The study consisted of a total of 46 patients, 32 of whom were using nasal steroids and 14 belonging to the C group. It was found that global value in MF group decreased from 100.9 ± 7.7 to 99.6 ± 7.6 in the 3rd month and ACD in MF group decreased from 3.2 ± 0.4 mm to 2.9 ± 0.4 mm in the 1st month, both to be found statistically significant (p = 0.037 and p = 0.001 respectively). During the RNFL thickness measurements of patients, it was found that Temporal (T) segment in FP group decreased from 82.1 ± 13.8 to 81.7 ± 13.3 in the first month and T segment in MF group decreased from 72.8 ± 12.0 to 71.3 ± 10.2 in 3 months, both decreases to be found statistically significant (p = 0.047 and p=0.003 respectively). It was found that IOP in FP group increased from 15.3 ± 3.6 mm Hg to 17.7 ± 4.1 mm Hg in the 3rd month hence found to be statistically significant (p = 0.006). CCT in FP patients was found to be significantly higher in the 3rd month (p = 0.025). Conclusions: As a result of our study, it was found that nasal steroid usage in patients with a family history of glaucoma may cause an increase in IOP and thinning of the RNFL.Öğe Elongation and aberrant articulation of cervical transverse processes mimicking osteochondroma(Elsevier Science Inc, 2015) Ünlü, Elif Nisa; Büyükkaya, Ayla; Ünlü, İlhan; Boran, Mertay; Güneş, Harun…Öğe Evaluating the effect of nasal septoplasty on atrial electromechanical features(W B Saunders Co-Elsevier Inc, 2019) Kayapınar, Osman; Kaya, Adnan; Özde, Cem; Cebeci, Derya; Ünlü, İlhanBackground: Recent studies have demonstrated that right ventricular (RV) dysfunction and increased pulmonary artery pressure may be frequent in patients with upper airway obstruction. In this study, we evaluated atrial conduction delays in patients with upper airway obstruction secondary to nasal septum deviation (NSD). Methods: A total of 32 patients with upper airway obstruction secondary to NSD undergoing a septoplasty procedure were enrolled in this study. Preoperative electrocardiography and transthoracic echocardiography were performed in all patients who underwent surgery. The mean pulmonary artery pressure (mPAP) and atrial conduction time (ACT) were recorded before and 6 months after the surgical procedures. Results: The PAP was significantly lower postoperatively than preoperatively (20.75 +/- 4.83 vs. 24.68 +/- 5.26; P < 0.001). The postoperative Electromechanical Delay of Mitral septal wall (EMD-MS) value was significantly lower than that preoperatively (46.20 +/- 8.5 vs. 40.5 +/- 9.9; P < 0.001). The postoperative Electromechanical Delay of Mitral lateral wall (EMD-ML) value decreased significantly compared to the preoperative period (46.3 +/- 7.4 vs. 40.6 +/- 9.3; P < 0.001). The postoperative Electromechanical Delay of Tricuspit lateral wall (EMD-TL) value was significantly lower than that preoperatively (43.8 +/- 7.0 vs. 38.1 +/- 9.1; P < 0.001). There was no significant change in pre- or postoperative measurements of inter- and intra-atrial conduction delays. Conclusions: We demonstrated that upper airway obstruction secondary to NSD causes a significant increase in mPAP and a significant delay in ACT, which improved after nasal septoplasty. According to these results, we conclude that upper airway obstruction may be an important risk factor for pulmonary arterial hypertension, RV dysfunction, and atrial arrhythmias, especially in unoperated cases.Öğe Evaluation of middle ear pressure in the early period after adenoidectomy in children with adenoid hypertrophy without otitis media with effusion(W B Saunders Co-Elsevier Inc, 2015) Ünlü, İlhan; Ünlü, Elif Nisa; Kesici, Gülin Gökçen; Güçlü, Ender; Yaman, Hüseyin; İlhan, Ethem; Memiş, MehmetObjective: Our aim was to analyze the changes in middle ear pressure in the early period after adenoidectomy in children with adenoid hypertrophy without otitis media with effusion. Methods: This prospective, descriptive study was performed on 64 patients (with normal tympanic membranes and tympanograms) undergoing adenoidectomy or adenotonsillectomy. All patients were operated by single experienced team using curettage technique. First tympanometry was done on the day before surgery. Tympanometry was repeated on the first-, third-, and seventh-day after the operation. Patients are separated into two groups according to age as patients younger than 6 years (Group A) and patients older than 6 years (Group B). All data were separately evaluated for each ear using Jerger Classification. Results: Of the 64 patients included in the study, 35 were male and 29 were female, and the average age was 91.01 +/- 37.4 (35-178) months. Pathological decreases in the middle ear pressures of at least one ear were determined in 48 (75%) patients on the first postoperative day and in 10 (15.6%) patients on the third postoperative day. Middle ear pressures returned to preoperative values by the seventh postoperative day except in two patients. There were statistically significant differences (p <0.0001) among preoperative and first, third, and seventh postoperative day mean middle ear pressure. There were no statistically significant differences between Groups A and B in terms of tympanometry values of both ears obtained preoperatively and on the first, third, and seventh postoperative day. Conclusion: In our study, temporary eustachian dysfunction and aural fullness occur in the early period after adenoidectomy and/or adenotonsillectomy. This situation may be due to post-surgery clots and edema in nasopharynx. We consider that tubal orifice can be exposed to surgical trauma as adenoidectomy surgeries are done by curettage technique. There is a need for comparative studies using microdebrider or laser adenoidectomy accompanied by an endoscope. (C) 2015 Elsevier Inc. All rights reserved.Öğe Evaluation of nasal mucociliary clearance time in patients with Vitamin-D deficiency(Springer, 2019) Akcan, Fatih Alper; Dündar, Yusuf; Akcan, Hümeyra Bayram; Uluat, Ahmet; Cebeci, Derya; Ünlü, İlhanObjectivesThe main purpose of the current study was to investigate nasal mucociliary clearance time (NMC) in patients with Vitamin-D deficiency.MethodsA total of 55 patients with Vitamin-D deficiency and 32 controls were evaluated. NMC time was measured with subjective saccharine test and compared between study and control groups. In addition, NMC time was re-evaluated after Vitamin-D replacement protocol in patients with Vitamin-D deficiency.ResultsThe mean 25(HO)Vitamin-D levels were 14.324.23ng/mL (7-24.6) and 29.38 +/- 7.05ng/mL (25-53.8) in study and control groups, respectively (p<0.001). The mean NMC time was 11.15 +/- 3.05 (6.3-17.6) and 8.40 +/- 2.33 (6-13.2) in study and control groups, respectively (p<0.001). The mean 25(HO)Vitamin-D level after the replacement protocol was 33.38 +/- 10.03 and the mean NMC time was 9.56 +/- 2.54 (p<0.001).Conclusion The mean NMC time was significantly increased in patients with Vitamin-D deficiency which can be corrected after Vitamin-D replacement protocols. The prolonged mucociliary clearance might be one of the pathophysiologic pathways at increased upper respiratory tract infections, and sinonasal and ear infections in patients with Vitamin-D deficiency.Öğe An interesting combination of anterior and posterior arch defects of atlas(Elsevier Science Inc, 2016) Ünlü, Elif Nisa; Aydın, Leyla Yılmaz; Ünlü, İlhan; Sönmez, Feruza Turan…Öğe Is there a Risk of Hearing Loss in Dental Technicians? A Case Control Study(2019) Kesici, Gülin Gökçen; Ünlü, İlhan; Baştürk, Arzu; Tutkun, EnginAim: Dental technicians are exposed to noise and chemical hazards that may lead to hearingloss in workplace. The aim of this study is to investigate the hearing loss risk of dentaltechnicians working in dental laboratories.Material and Methods: A hundred and five dental laboratory technicians who applied toAnkara Occupational Diseases Hospital for periodic check and 120 control subjects wereincluded in the study. All of the subjects in both the dental technician and control groups weremale. Audiograms of dental laboratory technicians was compared with audiograms of controlsubjects. Mann Whitney-U test and Spearman correlation analysis were used for statisticalanalysis of data.Results: The hearing threshold values of the dental technicians at all frequency in both earswere found to be significantly higher than the control group. There were statistically significantcorrelation between age and hearing thresholds at all frequencies (except at 250 Hz and 1000Hz) in dental technician group. There were statistically significant correlation between age andhearing thresholds at only 4000 Hz and 8000 Hz in control group. It was found that there werestatistically significant correlations between exposure time and hearing thresholds at 2, 4 and8 kHz frequencies in dental technician group.Conclusion: Results of this study indicate that hearing loss is a serious occupational healthproblem in dental technicians. Dental technicians are exposed to noise and chemical hazardsthat may constitute a risk for hearing loss. Dental technicians must take preventive measuresfor hearing loss during working.Öğe Parotis bezi tümörlerinin ayırıcı tanısında kesitsel radyolojik görüntülemenin ince iğne aspirasyon biyopsisi ve histopatolojik inceleme ile karşılaştırılması(2015) Ünlü, İlhan; Ulucanlı, Selim; İlhan, Ethem; Güçlü, Ender; Ünlü, Elif Nisa; Oktay, Murat; Kesici, Gülin GökçenAmaç: Bu çalışmada parotis bezi kitlelerinin ayırıcı tanısında kesitsel radyolojik görüntülemenin rolü araştırıldı. Hastalar ve Yöntemler: Ocak 2010 - Temmuz 2014 tarihleri arasında parotis bezinde kitle nedeniyle kliniğimizde ameliyat geçiren 35 hasta (21 erkek, 14 kadın; ort. yaş 50.011.5 yıl; dağılım 20-70 yıl) retrospektif olarak incelendi. Hastaların demografik verileri değerlendirildi. Kesitsel radyolojik görüntüler (bilgisayarlı tomografi ve manyetik rezonans görüntüleme) deneyimli bir radyolog tarafından tekrar değerlendirildi. Kesitsel radyolojik ayırıcı tanılar ince iğne aspirasyon biyopsisi (İİA B) ve histopatolojik tanı ile karşılaştırıldı. Bulgular: Histopatolojik incelemede iki hastada (%5.71) malignite tespit edildi. Bu hastalardan sadece birinde (%2.85) malignite İİA B ve kesitsel radyolojik görüntüleme ile gösterilebildi. Kesitsel radyolojik tanısı pleomorfik adenom olan 20 hastadan 12sinde (%60) tanı İİA B ile 14ünde (%70) histopatolojik olarak doğrulandı. Kesitsel radyolojik tanısı Warthin tümörü olan 12 hastanın altısında (%50) tanı İİA B ile yedisinde (%58.3) histopatolojik olarak doğrulandı. Kesitsel radyolojik bulgulara göre lenfadenopati tanısı konulan iki hastanın birinde (%50) tanı İİA B ile diğerinde histopatolojik olarak desteklendi. Kesitsel radyolojik bulgulara göre mukoepidermoid karsinom tanısı konulan bir hastaya ise İİA B ve histopatolojik inceleme ile Warthin tümörü tanısı konuldu. Sonuç: Kesitsel radyolojik görüntüleme parotis bezi tümörlerinin ayırıcı tanısı için tek başına yeterli değildir. Bu yöntem İİAB ile birlikte kullanıldığında daha doğru sonuçlar elde edilebilir.Öğe Pediatric Tracheotomies: A 5-Year Experience In 152 Children(Deomed Publ, Istanbul, 2018) Akcan, Fatih Alper; Dündar, Yusuf; Uluat, Ahmet; Cebeci, Derya; Sungur, Mehmet Ali; Salman, Nergis; Ünlü, İlhanObjective: To analyze the indications, complications, and outcomes of pediatric tracheotomies. Material and methods: All tracheotomies performed in a tertiary referral center between January 2011 and December 2015 were reviewed retrospectively. Demographic characteristics of patients, types of referral to hospital, tracheotomy indications, preoperative evaluation findings, surgical technique, postoperative care and complications, discharge and follow-up results were analyzed. Results: A total of 152 pediatric patients underwent tracheotomy at our hospital during this five year period. The median age of patients at the time of tracheotomy was 15.8 months, ranging from 24 days to 17 years. Of the 152 patients, 91 had neurological diseases, 38 had cardiopulmonary diseases, 14 had craniofacial abnormalities, seven had upper airway obstruction, and two underwent tracheostomy for trauma. Eleven (7.2%) patients experienced early complications, and 15 (9.8%) experienced late complications. Twenty (13.1%) patients were decannulated during the follow-up period. Unfortunately, 9 patients (5.9%) died of primary disease and 3 patients (1.9%) died of tracheostomy-related complications Conclusions: The majority of procedures were performed for diseases leading to prolonged mechanical ventilator support such as neurological and cardiopulmonary diseases. This study demostrates the importance of tracheotomy indications, which are the main predictors of decannulation rates. The other significant predictor is pulmonary complications that may cause permanent dependence of mechanical ventilator support as a result of pulmonary failure.Öğe Pediatric Tracheotomies: A 5-Year Experience in Düzce University Medical Faculty(2015) Ünlü, İlhan; İlhan, Ethem; Ünlü, Elif Nisa; Ateş, Hakan; Gün, Emrah; Yaman, Hüseyin; Güçlü, EnderAmaç: Trakeotomi en eski cerrahi uygulamalardan biridir. Çocuklarda trakeotomi endikasyonları son dönemlerde değişmiştir. Günümüzde akut enfeksiyonlar yerine daha çok uzamış entübasyon, üst solunum yolu obstrüksiyonu, nöromüsküler ve kraniofasial anomalilere bağlı olarak trakeotomi uygulanmaktadır. Bu çalışmada amacımız, pediatrik olgularda trakeotomi endikasyonları ve komplikasyonları ile ilgili deneyimlerimizi sunmaktır. Yöntemler: Bu çalışmada Haziran 2010-Haziran 2015 tarihleri arasında trakeotomi açılan 17 çocuk hasta geriye dönük olarak değerlendirilmiştir. Hastaların yaşları, cinsiyetleri, trakeotomi endikasyonları, entübe kaldıkları süre, komplikasyonları ve son durumları kaydedilmiştir. Bulgular: Kliniğimizde 17 pediatrik hastaya trakeotomi uygulanmıştır. Taburcu olan hastalar 3 aylık rutin kontrollerle izlenmiştir. Hastaların 6'sı (%35.29) izlem süresince primer hastalıkları nedeniyle kaybedilmiştir. Bulardan biri (%5.88) yaşamla bağdaşmayan anomalileri bulunan bir günlük yenidoğandı. Trakeal travma nedeniyle bir hastaya (%5.88) acil trakeotomi uygulanmıştır. Hastalarımızdan biri (%5.88) dışında hiçbiri dekanüle edilememiştir. Bir hastamızda kazara dekanülasyon, bir hastamızda da ameliyat sahasında kanama olmuştur. Toplam minör komplikasyon oranımız %11.76 iken, majör komplikasyonla karşılaşılmamıştır. Taburcu olan hastalardan ikisine (%11.76) rutin kontrollerinde stomanın daralması nedeniyle stoma genişletilmesi operasyonu uygulanmıştır. Sonuç: Günümüzde pediatrik olgularda trakeotomi ço- ğunlukla entübasyonun yapılamadığı üst solunum yolu obstrüksiyonlarında veya uzamış entübasyon durumlarında uygulanmaktadır. Özellikle uzun süreli entübasyon gereken hastaların ailelerine eğitim verilerek, hastaların taburcu edilip evde bakımları sağlanabilmektedir.
