Dalmaz, AslıhanDurmuş, SefaDulger, GorkemDülger, Başaran2021-12-012021-12-0120211301-40482147-835Xhttps://doi.org/10.16984/saufenbilder.737671https://app.trdizin.gov.tr/makale/TkRJd09UY3hNUT09https://hdl.handle.net/20.500.12684/9456In this work, firstly, CeO2 nanoparticles, which can be used as catalysts in many reactions, weresynthesized by preparing aqueous solution of cerium(III) nitrate hexahydrate in basic medium.In the second step, the synthesis of dimeric thio Schiff bases was carried out using two differentmethods. Effect of catalyst on some parameters such as reaction time and yield of product wereinvestigated. The antimicrobial activities of the ligands have been screened in vitro against theorganisms Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae (Gram negativebacteria), Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Bacilluscereus (Gram positive bacteria) and Candida albicans, C. tropicalis, C. guilliermondii, C.glabrata by Disc Diffusion and Microdilution methods. At the same time, antimicrobialactivities of ligands were compared to standard antibiotics (Cefotaxime, Amoxicillin/clavulanicacid, Posacanazole, Nystatin and Gentamicin). Generally, the results obtained in this researchshowed that all tested ligands exhibited more effect towards Gram positive bacteria andCandida species as compared to standard antibiotics.en10.16984/saufenbilder.737671info:eu-repo/semantics/openAccess[No Keywords]Article252364378