Aydın, MesutDumlu, TalhaAlemdar, RecaiKayapınar, OsmanCelbek, GökhanKarabacak, AhmetAtılgan, Zuhal Arıtürk2020-04-302020-04-3020121210-0668https://dx.doi.org/10.4149/endo_2012_03_147https://hdl.handle.net/20.500.12684/196PubMed ID: 22808906objectives. Te adipose tissue is an active immune organ. High sensitive C-reactive protein CRP (hs-CRP) is a strong independent predictor of a possible future myocardial infarction and stroke, and it has also been shown to be related to the sub clinical atherosclerosis. Te aim of this study was to investigate the relation between the body fat composition, metabolic syndrome, and the hs-CRP plasma levels. Methods. Total 246 consecutive Turkish subjects, admitted to the internal medicine clinic with the diagnosis of diabetes mellitus, insulin resistance or metabolic syndrome, were included into the study. Te total body fat composition was measured in every participant with a commercially available bio-impedance meter. Te hs-CRP levels, body composition parameters, and biochemical variables were compared. Results. Te hs-CRP levels increased in parallel with the body weight in Turkish subjects. Tis increase was significant especially in the women. Te waist circumference, body mass index (BMI), and body composition variables (visceral fat level, total body fat, and total body muscle mass) were significant correlates of the hs-CRP. Te waist circumference and BMI were independent predictors of the hs-CRP. Conclusion. Te waist circumference, BMI, and body composition variables (visceral fat level, total body fat and total body muscle mass) were significant correlates of the hs-CRP in Turkish adults. Body weight control may account for an important target especially in patients with the metabolic syndrome.en10.4149/endo_2012_03_147info:eu-repo/semantics/closedAccessBio-impedance meter; Body fat composition; Cardiovascular disease; Diabetes mellitus; High sensitive C-reactive protein; Metabolic syndromeArticle463147152Q3