Tunç, MuratArıcan, Nurdan2023-07-262023-07-2620201309-3878http://doi.org/10.18521/ktd.782163https://search.trdizin.gov.tr/yayin/detay/415948https://hdl.handle.net/20.500.12684/13291Objective: To investigate the demographic factors affecting the peripapillary nerve fiberthickness(PNFL) measured with optical coherence tomography(OCT) in diabetic patients.Methods: A total of 207 eyes of 104 diabetic patients (92 eyes of 46 males, 115 eyes of 58 female)who were followed-up between 2009-2013 were included. PNFL was measured with OCT in thesuperior, inferior, temporal and nasal quadrants and compared with demographic factors.Results: PNFL was found to be thinner in superior and inferior at the age of 60 years and abovecompared to under 60 years (p=0.004, p=0.001). There is a significant relationship between genderand the average PNFL only in inferior quadrants(p=0.006). There is no relationship betweenhypertension and the mean PNFL in 4 quadrants(p>0.05). Superior PNFL was decreased in eyeswith glaucoma compared to those without glaucoma(p=0.019). The mean PNFL in superior, inferiorand nasal patients with diabetes duration of more than 15 years decreased compared to those with 15years or less (p=0.048, p=0.020, p=0.020). Temporal PNFL was decreased in eyes withoutretinopathy compared to eyes with proliferative diabetic retinopathy(PDR) and non-PDR(p=0.025).Temporal PNFL was increased both in patients with diabetic macular edema(DME) and the patientstreated with panretinal photocoagulation (p=0.001, p=0.001). No correlation was found between themean PNFL in four quadrants with focal laser treatment(p>0.05).Conclusions: Age, gender, duration of diabetes, glaucoma, DME, PDR, non-PDR have an effect onPNFL, but HT and focal laser have not. In addition, the duration of diabetes and the presence ofdiabetic retinopathy(DR) should be taken into account when evaluating the progression of PNFLdefects in patients with both glaucoma and diabetes.en10.18521/ktd.782163info:eu-repo/semantics/openAccessArticle123456462415948