Akyüz, FilizUyanıkoğlu, AhmetErmiş, FatihArıcı, SerpilAkyüz, ÜmitBaran, BülentGül, Nurdan2020-05-012020-05-0120151007-93272219-2840https://doi.org/10.3748/wjg.v21.i10.3030https://hdl.handle.net/20.500.12684/6042Baran, Bulent/0000-0001-7966-2346; Uyanikoglu, Ahmet/0000-0003-4881-5244WOS: 000350689100021PubMed: 25780302AIM: To investigate the relationship between reflux and body mass index (BMI) in the asymptomatic obese population using the impedance-pH technique. METHODS: Gastroesophageal reflux is frequent in the obese population. However, the relationship between acid reflux and BMI in asymptomatic obese people is unclear. Forty-six obese (BMI > 25 kg/m(2)) people were enrolled in this prospective study. We evaluated the demographic findings and 24-h impedance pH values of the whole group. Gas, acid (pH < 4), weak acid (pH = 4-7) and weak alkaline (pH = 7) reflux parameters were analyzed. RESULTS: The mean age of patients was 49.47 +/- 12.24 years, and half of them were men. The mean BMI was 30.64 +/- 3.95 kg/m(2) (25.14-45.58 kg/m(2)). BMI of 23 was over 30 kg/m(2). Seventeen patients had a comorbidity (hypertension, diabetes mellitus, or ischemic heart disease). Endoscopic examination revealed esophagitis in 13 of the 28 subjects (10 Grade A, 3 Grade B). The subjects were divided into two groups according to BMI (< 30 and > 30 kg/m(2)). Demographic and endoscopic findings, and impedance results were similar in these two groups. However, there was a positive correlation between BMI and total and supine pH < 4 episodes (P = 0.002, r = 0.414; P = 0.000, r = 0.542), pH < 4 reflux time (P = 0.015, r = 0.319; P = 0.003, r = 0.403), and DeMeester score (P = 0.012, r = 0.333). CONCLUSION: Acid reflux is correlated with BMI in asymptomatic obese individuals.en10.3748/wjg.v21.i10.3030info:eu-repo/semantics/openAccessRefluxImpedanceObesity24-h pH-metryBody mass indexArticle211030303034WOS:000350689100021Q1Q2