Şengül, Eda Pepeİnal, Meltem AktayCeylan, AsiyeÜtebey, GültenÖzlü, Onur2020-04-302020-04-3020161300-0578https://hdl.handle.net/20.500.12684/169Objective: To compare the postoperative analgesic effects of a preemptive intravenous ketamine and lornoxicam in patients undergoing laparoscopic cholecystectomy. Method: A total of 60 ASA I-II patients were included in this study and divided into three groups. Patients in Group KE were given 0.5 mg kg-1 ketamine, Group L were given 8 mg lornoxicam and in Group C were given 2 mL saline before surgical incision. All cases underwent general anesthesia and received postoperative patient-controlled analgesia with tramadol. VAS (Visual Analogue Scale) scores, at 0.,15.,30.th minutes and I .,2.,6.,12.,24.th hours, tramadol consumption, time and amount of additional analgesia were recorded Results: VAS scores, at 0., 15., 30. minutes and first hour were lower in group KE and L than group C (p<0.001) and there wasn't any difference between group KE and L (p>0.05). There was no significant difference between three groups regarding VAS scores at 2, 6,12, 24.'h hours (p>0.05). Time to first analgesia was later in group L than group C and KE (p<0.05). There was no difference between groups regarding to additional analgesia requirement. Tramadol consumption was lower in group L than group C, and there was no difference between group KE and group C.Conclusion: Lornoxicam and ketamine reduced the early postoperative pain and lornoxicam reduced total tramadol consumption more effectively than ketamine.trinfo:eu-repo/semantics/closedAccessAnalgesia; Ketamine; Lornoxicam; Patient-controlled AnalgesiaArticle244252256Q4