Önmez, AttllaAltun, GulsahAkbaş, TürkayÖneç, Birgül2025-03-242025-03-2420222791-9250https://hdl.handle.net/20.500.12684/19796Tumor necrosis factor-alpha (TNF-?), which is produced by macrophages and activated T lymphocyte cells, plays a main role in inducing further stimulation of other inflammatory cells. Anti-TNF-? drugs are used for induction and preservation of remission in patients with Ankylosing spondylitis. Etanercept, which is one of the most used Anti-TNF-? drugs, has side effects such as cytopenia but isolated thrombocytopenia is an uncommon adverse event. We report the case of a 40-year-old man diagnosed with Ankylosing spondylitis who developed Etanercept-induced isolated thrombocytopenia.eninfo:eu-repo/semantics/openAccessThrombocytopenia|Ankylosing Spondylitis|adverse effect|biological agentsArticle212829