Sav, Nadide MelikeKosger, PelinCan, BetülÇetin, NuranUçar, BirsenAlataş, ÖzkanAkyüz, Fahrettin2023-07-262023-07-2620221342-17511437-7799https://doi.org/10.1007/s10157-021-02169-7https://hdl.handle.net/20.500.12684/12350Background The present study investigates cardiovascular risk and kidney damage in patients with solitary kidneys. Methods Included in the study were 40 children with a unilateral functioning kidney and 60 healthy controls, all of whom were evaluated for carotid intima-media thickness, ischemia-modified albumin and oxidative stress parameters, and 24-h ambulatory blood pressure monitoring. Results Serum creatinine and urine microalbumin levels were higher and creatinine clearance was lower in the patient group than in the control group, and serum ischemia-modified albumin, carotid intima-media thickness, aldosterone, plasma renin activity and blood pressure were all higher in the patient group than in the control group. In addition, the patient group was showed a non-dipper pattern. Conclusion Children with a normal functioning solitary kidney are likely at higher risk of developing cardiovascular disease and such patients should be followed closely before marked kidney impairment occurs.en10.1007/s10157-021-02169-7info:eu-repo/semantics/closedAccessSolitary Kidney; Cardiovascular Risk; Children; Carotid Intima-Media Thickness; Ischemia-Modified Albumin; 24-H Ambulatory Blood Pressure MonitoringIschemia-Modified Albumin; Blood-Pressure; Myocardial-Ischemia; Oxidative Stress; Heart-Failure; Disease; Binding; Marker; Assay; ProteinuriaArticle265415423350371262-s2.0-85123067673WOS:000743002500001Q2Q3