Özhan, HakanErden, İsmailOrdu, SerkanAydın, MesutÇağlar, OnurBaşar, CengizAlemdar, Recai2020-05-012020-05-0120100003-31971940-1574https://doi.org/10.1177/0003319710364216https://hdl.handle.net/20.500.12684/5886WOS: 000281677000014PubMed: 20395226Contrast-induced nephropathy (CIN) is associated with increased morbidity, extended hospital stay, and higher costs. We compared an atorvastatin plus N-acetylcysteine (NAC) regimen with NAC alone in patients undergoing coronary angiography. A total of 130 patients (mean age 54 +/- 10; 77 men) undergoing coronary angiography were studied. Seven CIN cases occurred in the NAC group and 2 in the atorvastatin + NAC group; this difference was not significant. Baseline mean creatinine and estimated glomerular filtration rate (eGFR) were similar between the 2 groups, whereas after the procedure there was a significant creatinine decrease and eGFR increase in the atorvastatin + NAC group. Change in creatinine (baseline creatinine-creatinine after the procedure) was also significantly higher in patients taking statin plus NAC. Atorvastatin may be effective in protecting patients undergoing coronary angiography from CIN.en10.1177/0003319710364216info:eu-repo/semantics/closedAccesscontrast-induced nephropathyatorvastatinN-acetylcysteineArticle617711714WOS:000281677000014Q2Q4