Uslu, EsmaBaşkan, ElifeBaşar, FeyzaTuran, HakanOktay, Murat2020-04-302020-04-3020162564-77842564-7040https://doi.org/10.5152/EurJTher.2016.015https://hdl.handle.net/20.500.12684/4086WOS: 000439240200015Discoid lupus erythematosus (DLE) is the most frequent form of cutaneous lupus erythematosus. It is typically located on sun-exposed areas, such as forehead, nose, cheeks, eyelids, scalp, neck, presternal area, and the extensor aspects of extremities. Eyelid involvement is rare and usually it is accompanied with skin lesions elsewhere on the body. On this localization, DLE can mimic blepharoconjunctivitis, allergic dermatitis, psoriasis, lichen planus, basal cell carcinoma, granuloma annulare, tinea faciale, and eyelid edema. On the periorbital region, therefore, if one of these diseases is pre-diagnosed but there is no response to the treatment, DLE should be considered in the differential diagnosis. Here, the case of a 25 year-old male patient with discoid lupus erythematosus that has a peri-orbital location is presented, along with the response to topical tacrolimus cream treatment.tr10.5152/EurJTher.2016.015info:eu-repo/semantics/closedAccessDiscoid lupusperiorbitaltacrolimusArticle223179181N/A