Coşkun, AbdurrahmanGünal, ÖmerŞahin, İbrahimAslaner, ArifYıldırım, ÜmranYavuz, Özlem2020-05-012020-05-0120071386-6346https://doi.org/10.1111/j.1872-034X.2007.00088.xhttps://hdl.handle.net/20.500.12684/5613Coskun, Abdurrahman/0000-0002-1273-0604;WOS: 000248729900010PubMed: 17517073Aim: To evaluate the protective effect of L-carnitine on liver tissue preserved in University of Wisconsin (UW) solution. Methods: Twenty Wistar Albino rats were divided into two groups, a control (UW) group and a UW Plus L-carnitine group. Retrieved liver grafts were preserved in UW and UW Plus L-carnitine solutions at +4 degrees C. Preservation solution samples were assessed at 2, 24, 36, and 48 h to measure alanine aminotransferase and acid phosphatase activity. Tissue injury was scored on paraffin sections. Results: No micro or macrovacuolar fat droplets were observed in the tissue slices. L-Carnitine effectively decreased enzyme release when added to UW solution (P < 0.05). Conclusion: in addition to fatty liver, L-carnitine might be a metabolic adjunct in preservation solutions for non-fatty liver within UW solution.en10.1111/j.1872-034X.2007.00088.xinfo:eu-repo/semantics/closedAccesscold ischemiaL-carnitineliver preservationtransplantationUniversity of WisconsinArticle378656660WOS:000248729900010Q1Q3