Turan, HakanTuran, Ayşegül2020-04-302020-04-3020121300-0292https://doi.org/10.5336/medsci.2010-22303https://hdl.handle.net/20.500.12684/3809WOS: 000313378300037Nicolau syndrome is a rare and local complication of aberrant intramuscular injections of various drugs. It is characterized by a necrotic or hemorrhagic plaque, which follows a pale then consequently an erythematous macule on the injection area. It usually heals by leaving an atrophic scar. The exact pathogenesis is unknown. Nonetheless, a possible cause is the development of arterial spasm following tissue necrosis after the drug is injected into a blood vessel by mistake. Here, we presented a case of Nicolau syndrome occurring after the injection of diclofenac to the thigh region.en10.5336/medsci.2010-22303info:eu-repo/semantics/openAccessDiclofenacinjections, intramuscularArticle32514371439Q4N/A