Gültekin, Hazal EzgiÖner, Ezgiİlhan, MirayKarpuz, Merve2023-07-262023-07-26202297803239186579780323919531https://doi.org/10.1016/B978-0-323-91865-7.00018-3https://hdl.handle.net/20.500.12684/12838Nanovesicular systems such as liposomes, niosomes, polymersomes, ethosomes, transfersomes, and extracellular vesicles are well-recognized carriers for the effective delivery and controlled release of drugs, genes, phytocompounds, imaging agents, and theranostics. With the intravenous administration of nanovesicles as targeted drug carriers, the bioavailability of active compounds is increased, while side effects at the sites of action are reduced. In this chapter, the nanovesicles are classified based on their structure and the type of drug to be loaded. The remarkable developments in the intravenous administration of nanovesicles are investigated and reviewed. In addition, usage areas of intravenous nanovesicles are highlighted regarding their applications in the treatment of diseases, gene therapy, and imaging. This chapter also provides insight into the place of intravenous nanovesicles in clinical applications by discussing their advantages, disadvantages, and potential challenges. © 2022 Elsevier Inc. All rights reserved.en10.1016/B978-0-323-91865-7.00018-3info:eu-repo/semantics/closedAccessethosomesgene therapyIntravenous drug administrationliposomesnanovesiclesniosomesphytosomespolymersomestheranosticstransfersomesBook Chapter1151482-s2.0-85142811381