Başbuğ, DeryaBaşbuğ, AlperGülerman, Cavidan2020-04-302020-04-3020170017-00112543-6767https://doi.org/10.5603/GP.a2017.0061https://hdl.handle.net/20.500.12684/3521WOS: 000405108100009PubMed: 28727133Objectives: The purpose of this study was to determined the predictive value of maternal serum alpha-fetoprotein (MSAFP) as a marker for adverse pregnancy outcomes. Material and methods: This study was carried out at Dr. Zekai Tahir Burak Women's Health Education and Research Hospital between 2009 and 2010. This study included a total of 1,177 pregnant women, including 170 in the study group and 1,007 in the control group. Pregnancy outcomes and characteristics were analyzed with regard to the MSAFP value. Results: Gestational week, birth weight and APGAR scores were significantly lower in the elevated MSAFP group (p < 0.001). Adverse pregnancy outcomes, such as preterm delivery, preterm premature rupture of membranes (PPROM), oligohydramnios and intrauterine growth restriction (IUGR) rates were increased in the elevated MSAFP group. Conclusions: Although ultrasound outweighs as a screening method for neural tube defects and non-invasive prenatal testing outweighs for aneuploidy screening MSAFP level in the second trimester is still an important predictor for poor maternal/fetal outcomes.en10.5603/GP.a2017.0061info:eu-repo/semantics/openAccessalpha-fetoproteinadverse pregnancy outcomeprenatal testsArticle886325330WOS:000405108100009Q3Q4