Parlar, HakanArikan, Ali AhmetOnmez, Attila2021-12-012021-12-0120210102-76381678-9741https://doi.org/10.21470/1678-9741-2020-0163https://hdl.handle.net/20.500.12684/10643Introduction: This study investigated the role of the neutrophillymphocyte ratio (NLR), the perioperative changes in NLR (deltaNLR), the platelet-lymphocyte ratio (PLR), and the platelet count in predicting acute kidney injury (AKI) following coronary artery bypass grafting (CABG) during hospital stay. Methods: The records of 396 patients with preoperative creatinine < 1.5 mg/dl undergoing isolated CABG between October 2015 and October 2019 were reviewed retrospectively. Diagnosis of AKI was based on the Kidney Disease Improving Global Outcomes definition. Demographic data, operative data, inhospital mortality, preoperative NLR, PLR, and platelet counts were compared between patients with (AKI group) and without (nonAKI group) postoperative AKI. Additionally, NLR, delta-NLR, and PLR values were calculated daily for the first four postoperative days. A subsequent AKI group was formed for the first four postoperative days by excluding patients diagnosed with AKI. The daily and overall predictivity of the markers for AKI are investigated. Results: AKI was present in 86 patients during the postoperative period, while 310 patients had normal postoperative renal functions. NLR, delta-NLR, and PLR on the first four postoperative days (P<0.001 for all) were significantly associated with the development of AKI in subsequent days. Multivariate analysis identified postoperative NLR (odds ratio 1.17, 95% confidence interval 1.11-1.23; P<0.001) as an independent predictor of AKI. PLR lost its significant association with AKI at the values measured at discharge from hospital (P>0.05). Conclusion: NLR values measured on the first four days postoperatively are a useful tool in predicting AKI during hospital stay following CABG.en10.21470/1678-9741-2020-0163info:eu-repo/semantics/openAccessCoronary Artery BypassAcute Kidney InjuryNeutrophilsLymphocytesPlatelet CountLength of StayPatient DischargeTo-Lymphocyte RatioCardiac-SurgeryNeutrophilPlateletArticle363354364343879732-s2.0-85112676294WOS:000674648100011Q3Q4