Koçer, AbdulkadirEryılmaz, MehmetTutkan, HavaErcan, NurtenKüçükbayrak, Zeynep Seçkin2020-05-012020-05-0120121537-744Xhttps://doi.org/10.1100/2012/791460https://hdl.handle.net/20.500.12684/6205Kocer, Abdulkadir/0000-0003-2866-555XWOS: 000305424900001PubMed: 22666153Objective and Aim. An imbalance of the sympathetic system may explain many of the clinical manifestations of the migraine. We aimed to evaluate P-waves as a reveal of sympathetic system function in migraine patients and healthy controls. Materials and Methods. Thirty-five episodic type of migraine patients (complained of migraine during 5 years or more, BMI < 30 kg/m(2)) and 30 controls were included in our study. We measured P-wave durations (minimum, maximum, and dispersion) from 12-lead ECG recording during pain-free periods. ECGs were transferred to a personal computer via a scanner and then used for magnification of x400 by Adobe Photoshop software. Results. P-wave durations were found to be similar between migraine patients and controls. Although P WD (P-wave dispersion) was similar, the mean value was higher in migraine subjects. P WD was positively correlated with P max (P < 0.01). Attacks number per month and male gender were the factors related to the P WD (P < 0.01). Conclusions. Many previous studies suggested that increased sympathetic activity may cause an increase in P WD. We found that P WD of migraine patients was higher than controls, and P WD was related to attacks number per month and male gender. Further studies are needed to explain the chronic effects of migraine.en10.1100/2012/791460info:eu-repo/semantics/openAccessArticleWOS:000305424900001N/AQ1