Özçelik, DeryaSağlam, İbrahimSılan, FatmaSezen, GülbinÜnveren, Toygar2020-04-302020-04-3020081055-66561545-1569https://doi.org/10.1597/06-249https://hdl.handle.net/20.500.12684/2722Saglam, Ibrahim/0000-0002-1706-4444WOS: 000256241500005PubMed: 18452356Objective: We report that a 4-year-old boy presented with right unilateral complete cleft lip and palate, right anophthalmos, left congenital nystagmus, absence of the vomer bone, mental-motor retardation, and normal lymphocyte karyotype (46, XY). Methods: For reconstruction of the deformities, we performed cleft lip repair by Millard's rotation-advancement technique and planned cleft palate repair. Conclusions: This combination of cleft lip and palate, anophthalmos, congenital nystagmus, absent vomer bone, and mental-motor retardation has not, to our knowledge, previously been described. We suggest that this represents either another case of the rare Fryns "anophthalmia-plus" syndrome or a new syndrome.en10.1597/06-249info:eu-repo/semantics/closedAccessanophthalmiacleft lip/palateFryns anophthalmia-plusmicrophthalmianystagmussingle central incisor toothvomerArticle453256260WOS:000256241500005Q2Q3